Synbio Technologies introduces CRISPR RNP-mediated cell gene editing services, which build on advanced technology and an experienced team, offering end-to-end solutions.

Case Overview
Synbio Technologies engineered a homozygous TLR8 gene point mutation (cDNA position: ttgGta → CtACtC) in human THP-1 monocytic cells using CRISPR-Cas9 homology-directed repair (HDR).
Validated through PCR and Sanger sequencing, this isogenic model enables mechanistic studies of TLR8 signaling dysregulation in innate immunity and inflammation research.



We specialize in providing advanced genome editing tools and services:
• Mammalian Cell Gene Editing
• Single guide RNA (sgRNA) design and synthesis
• Efficient sgRNA library synthesis
• Human Gene CRISPR-KO Vectors
 
 
 
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Synbio Technologies LLC
9 Deer Prk Dr., Suite J-25, Monmouth Junction, NJ 08852, USA